阿尔茨海默病大脑退行性障碍。它发生在中后期的成年生活,破坏大脑皮层神经元和连接,导致脑质量的重大损失。三个阶段的疾病是公认的:临床前,轻度认知障碍,和老年痴呆,这是老年人中最常见的痴呆症。全世界大约有3560万人在2010年患老年痴呆症。阿尔茨海默病的进展从短期记忆障碍进一步记忆丧失;恶化的语言、知觉和运动技能;情绪不稳定;在晚期,反应迟钝,失去流动性和控制身体的功能。死亡后随之而来疾病持续2 - 20年。最初在1906年描述阿尔茨海默(1864 - 1915)德国神经病理学家参照一个55岁的人,被视为早老性痴呆、阿尔茨海默病是现在公认会计的老年性痴呆曾经认为正常老化。 The 10% of cases that begin before age 60 appear to result from an inherited mutation. Early detection is based on the presence of biomarkers (physiological changes specific to or indicative of a disease) and on diagnostic imaging, with visualization of neuritic plaques and neurofibrillary tangles in the brain providing evidence of the disease. No cure has been found. Most treatment targets the depression, behavioral problems, and sleeplessness that often accompany the disease.
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